Kim Possible

Christy Carlson Romano

Kim Possible (voice)

Will Friedle

Ron Stoppable (voice)

Nancy Cartwright

Rufus (voice)

Tahj Mowry

Wade Load (voice)

John DiMaggio

, Dr. Drakken (voice), Dr. Drakken / Motor Ed (voice), Dr. Drakken / Heinrich (voice), Dr. Drakken / Student (voice), Camp Counselor (voice), Blumberg / Phone Guy (voice), Ferrett Fan (voice), Dr. Drakken / Dr. Zeruda (voice), Dr. Drakken / Mr. Peevey (voice), Snow Beast / Pig Man / Bird Man (voice), Motor Ed (voice), Dr. Drakken / Bartholomew Lipsky (voice), Motor Ed / Dr. Drakken (voice), Dr. Drakken / M.C. Honey's Posse (voice)

Nicole Sullivan

Shego (voice), , Shego / Computer Voice (voice), Shego / Miss Go (voice)

Patrick Warburton

Steve Barkin (voice), Steve Barkin / Chief Barkin (voice)

Kirsten Storms

Bonnie Rockwaller (voice)

Jean Smart

Dr. Ann Possible (voice), Dr. Anne Possible (voice), Dr. Ann Possible / Tutor Woman (voice)

Raven-Symoné

Monique (voice)

Gary Cole

Dr. James Possible (voice)

Tara Strong

Britina (voice), Tara (voice), Additional Voices (voice), Female Gamer (voice), Tara / Sean (voice), Tara / Cheer Camp Counselor / Band Camp Kid (voice), Joss Possible (voice), Espadrille (voice), Penny (voice), Tara / Yearbook Girl (voice)